When levels are checked in a healthy individual not experiencing stressors on the system, NAC is found to increase the free cysteine although it leaves the total cysteine and glutathione levels unchanged
You can support this pathway with vitamin B6 as a cofactor, increase cysteine containing foods - eggs, pulses, seeds, meat and fish, or consider a supplement of NAC - N-acetyl cysteine
Wang B, Zhu S, Guo M, Ma R-D, Tang Y-L, Nie Y-X, et al
Cosmetics (MDPI) (2015) 5
People on anticoagulants, because of vascular and nitric-oxide effects
This 'failure to translate' is likely to be related primarily to our incomplete understanding of the pathogenic mechanisms underlying PD, and excessive reliance on data from toxin-based animal models to judge which agents should be selected for clinical trials